Dean Prof. CHEN Jianguo's CV



Name: Jian-Guo CHEN. 

Tel num.: (Cell phone)0086-13871250828, (O)0086-27-- 83692636


Present address: #13 Hangkong Road, School of Basic Science,

  Tongji MedicalCollege,Huazhong University of  

                            Science & Technology, Wuhan,Hubei430030, China   

Educationand Professional TrainingExperience

Oct.1998-Dec.2001: Postdoctoral Associate,Dr. ToshinoriHoshi’s laboratory, Dept. of Physiology and Biophysics, College of Medicine,The University of Iowa(USA).

Oct. 1996-Sept.1998:Ph.D, Dr. JuergenSandkuhler’s laboratory, II. Physiology Institute, The Medical College,TheUniversity of Heidelberg (Germany).

Nov.1995-Sept.1996:Visiting scholar, Prof.Dr. Joachim W. Deitmer’s laboratory,Schoolof Biology, The University of Kaiserslautern (Germany).

Sept.1987-July,1990: M. Sci., Dr. Zhi-Wang Li’s laboratory,Tongji MedicalCollege, Huazhong University of Science and Technology(China).

Sept.1980-July,1985:M.D., School of Medicine, Hubei University of Science and Technology(China).

Working Experience

Aug. 2015-present: Vice-President, Huazhong University of Science & Technology (HUST)

Dean, Tongji Medical College of HUST

Oct. 2011-Aug. 2015: Assistant-President of HUST

May 2008-Aug. 2015:Chief, Office of Research and Development of HUST

Jan.2002-present:Professor, Chairman, Department of Pharmacology,Tongji Medical College, HuazhongUniversity of Science & Technology(HUST, China)

2004: Awarded as Distinguished Young Scientist bythe National Natural Science Foundation of China(NSFC)

2007: Endowed Distinguished Professor of Yangtze Program of MOE, China

2013: Chief Scientist,the National Basic Research Program of China (973 Program)

Sep. 1990-Oct.1995:Lecturer, Department of Pharmacology,Tongji MedicalCollege, HuazhongUniversityof Science and Technology(China).

Activities in Scientific Society

Vice President, Chinese Pharmacological Society

President, the Pharmacological Society of Hubei Province

Vice President, the Sino-Germany Association of Medicine in Hubei Province

Member of the Society for Neuroscience, USA


Major depressivedisorder, drug addiction and therapy

Selected Publications:(corresponding authors are marked with *)

1.Fan H, Wu PF, Zhang L, Hu ZL, Wang W, Guan XL, Luo H, Ni M, Yang JW, Li MX, Chen JG*, Wang F*. Methionine Sulfoxide Reductase A Negatively Controls Microglia-mediated Neuroinflammation via Inhibiting ROS/MAPKs/NF-κB Signaling Pathways through a Catalytic Antioxidant Function.Antioxid Redox Signal.2015 Jan 20. [Epub ahead of print]

2.Luo Y, Zhou J, Li MX, Wu PF, Hu ZL, Ni L, Jin Y,Chen JG*, Wang F*. Reversal of aging-related emotional memory deficits by norepinephrine via regulating the stability of surface AMPA receptors.Aging Cell. 2015 Jan 7. doi: 10.1111/acel.12282.

3.Yu XW, Hu ZL, Ni M, Fang P, Zhang PW, Shu Q, Fan H, Zhou HY, Ni L, Zhu LQ,Chen JG*, Wang F*. Acid-sensing ion channels promote the inflammation and migration of cultured rat microglia.Glia. 2015;63(3):483-96.

4.Lu HF, Wu PF, Yang YJ, Xiao W, Fan J, Liu J, Li YL, Luo Y, Hu ZL, Jin Y, Wang F*,Chen JG*. Interactions between N-ethylmaleimide-sensitive factor and GluR2 in the nucleus accumbens contribute to the expression of locomotor sensitization to cocaine.J Neurosci. 2014;34(10):3493-508.

5.Jiang B, Wang F, Yang S, Fang P, Deng ZF, Xiao JL, Hu ZL,Chen JG*. SKF83959 Produces Antidepressant Effects in a Chronic Social Defeat Stress Model of Depression through BDNF-TrkB Pathway.Int J Neuropsychopharmacol. 2014 Dec 7. pii: pyu096. doi: 10.1093/ijnp/pyu096. [Epub ahead of print]

6.Jiang B, Wang W, Wang F, Hu ZL, Xiao JL, Yang S, Zhang J, Peng XZ, Wang JH,Chen JG*. The Stability of NR2B in the Nucleus Accumbens Controls Behavioral and Synaptic Adaptations to Chronic Stress.Biol Psychiatry. 2013;74(2):145-55.

7.Li YK, Wang F, Wang W, Luo Y, Wu PF, Xiao JL, Hu ZL, Jin Y, Hu G,Chen JG*. Aquaporin-4 Deficiency Impairs Synaptic Plasticity and Associative Fear Memory in the Lateral Amygdala: Involvement of Downregulation of Glutamate Transporter-1 Expression.Neuropsychopharmacology. 2012 Jul;37(8):1867-78. doi: 10.1038/npp.2012.34.

8.Jiang B, Xiong Z, Yang J, Wang W, Wang Y, Hu ZL, Wang F*,Chen JG*. Antidepressant-like effects of Ginsenoside Rg1 produced by activation of BDNF signaling pathway and neurogenesis in the hippocampus.Br J Pharmacol. 2012; 166(6):1872-87.

9.Wang Y, Guan XL, Wu PF, Wang CM, Cao H, Li L, Guo XJ, Wang F, Xie N, Jiang FC,Chen JG*. Multifunctional mercapto-tacrine derivatives for treatment of age-related neurodegenerative diseases.J Med Chem. 2012 Apr 12;55(7):3588-92.

10.Wang W, Wang F, Yang YJ, Hu ZL, Long LH, Fu H, Xie N,Chen JG*. The flavonoid baicalein promotes NMDA receptor-dependent long-term potentiation and enhances memory.Br J Pharmacol. 2011;162(6):1364-79.

11.Yang YJ, Wu PF, Long LH, Yu DF, Wu WN, Hu ZL, Fu H, Xie N, Jin Y, Ni L, Wang JZ, Wang F*,Chen JG*. Reversal of aging-associated hippocampal synaptic plasticity deficits by reductants via regulation of thiol redox and NMDA receptor function.Aging Cell. 2010; 9(5):709-21.

12.Huang C, Hu ZL, Wu WN, Yu DF, Xiong QJ, Song JR, Shu Q, Fu H, Wang F*,Chen JG*. Existence and distinction of acid-evoked currents in rat astrocytes.Glia. 2010; 58(12):1415-24

13.Mao LM, Wang W, Chu XP, Zhang GC, Liu XY, Yang YJ, Haines M, Papasian CJ, Fibuch EE, Buch S,ChenJG*, Wang JQ*. Stability of surface NMDA receptors controls synaptic and behavioral adaptations to amphetamine.Nat Neurosci.2009; 12(5):602-10.